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Tuesday 01-12-2015

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ECO highlights the future of poultry antimicrobial


ECO Animal Health will be showcasing its innovative antimicrobial treatment, Aivlosin®, on its booth at IPPE in Atlanta, 27-29 January 2015.

The Aivlosin products contain the novel macrolide, tylvalosin, which has been shown to have a number of benefits in poultry. In addition, the low dose rates and short treatment regimens support the responsible and judicious use of antibiotics.

Tylvalosin, the active substance in the Aivlosin formulations, is one of the most potent ones against poultry mycoplasma spp. Peak plasma levels are achieved within two hours of administration and tylvalosin quickly concentrates at the site of infection. It has also been shown to be concentrated in the cells of the specific immune system which fight infection.

According to Global Marketing Director at ECO Animal Health, Marc Coulier, this unique profile is rapidly making the Aivlosin products the treatment of choice for poultry veterinarians and producers for respiratory disease.

The poultry industry is starting to realise the benefits of using a product like Aivlosin for ensuring flock health and aiding a speedy recovery from the production losses associated with mycoplasmal infections. We have seen a big increase in interest in Aivlosin in all parts of the world.

Aivlosin is particularly being used for targeted treatment strategies for respiratory and enteric diseases such as mycoplasmosis, ORT (caused by Ornithobacterium rhinotracheale) and necrotic enteritis in poultry,” he said.

Part of the success of Aivlosin is due to its activity against bacteria both inside and outside cells and its bactericidal effect on Mycoplasma spp. Aivlosin is available as a medicated premix and as water soluble granules. The latter formulation allows birds to be dosed easily and quickly in response to any disease outbreak.

At a time when everyone is looking more closely at the use of antimicrobials in animal production, ECO Animal Health supports the responsible use of these essential drugs, and Aivlosin is an excellent example of that principle in action. This is an antimicrobial which is not used in human medicine and which is used for a rapid response only as and when issues arise. Aivlosin’s effective low dosage regimen is attractive for poultry meat retailers and thus, reflects the direction in which the industry is now moving,” added Coulier.

The ECO Animal Health booth [A2 445] will have more detailed information on the use of Aivlosin for poultry and for pigs.

 

Aivlosin® is available in a number of international markets under the brand name of Valosin®


Aivlosin® and Valosin® are registered trademarks of ECO Animal Health Ltd., London, United Kingdom.


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Notes to editor:

For further press information please contact Mike Keeler or Nic Daley on +44 (0)20 8647 4467.

ECO highlights the future of poultry antimicrobials



Friday 20-02-2015

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Responsible treatment of ileitis


Responsible use of antibiotics can save swine producers money and improve the control of common swine diseases such as ileitis (PPE), according to the global animal health company, ECO Animal Health.

The company believes that the development of anti-microbials, such as its second generation macrolide Aivlosin®, containing tylvalosin (TVN), can provide improved treatment options. As a modern antibiotic it meets the requirements of judicious use of antimicrobials.

Tylvalosin is more lipophilic than older generation macrolides such as tylosin.  Studies have shown that tylvalosin concentrates within target tissue cells very rapidly, resulting in far higher intracellular concentrations of active drug just 4 hours after dosing. The concentration of active drug in small intestinal tissue is over three times higher than the blood concentration just 2 hours after administration.

According to Andrew Buglass, European Sales Director from ECO Animal Health, the product’s profile makes Aivlosin ideally suited to responsible use.

“The improved product profile means that a shorter, 10-day course of in-feed treatment with Aivlosin should treat sub-clinical ileitis as effectively as 21 days of in-feed treatment with tylosin. In fact, a randomised trial on a well-managed European swine farm showed that controlling ileitis in pigs with Aivlosin resulted in 2.1kg extra carcass weight compared to using tylosin. Importantly the total amount of antibiotic active ingredient was reduced by 58% per pig for the Aivlosin treated group compared to the tylosin treated animals” he said.

440 pigs with sub-clinical ileitis were enrolled in the study. Seroconversion  diagnosed by ELISA, occurred in pigs on this farm between 10 and 14 weeks of age. Treatment was timed to coincide with the transfer of animals to the fattening house and early infection with Lawsonia intracellularis. 

“As L. intracellularis bacteria accumulate in the intestinal cells, the ability of tylvalosin to penetrate and concentrate within these epithelial cells is an asset  when treating ileitis. Targeting the correct time to apply a shorter-course treatment is a step in the right direction if we want to use antibiotics in a more judicious way.

“Since the EU ban on the use of antibiotics as growth promoters, ileitis remains endemic on most swine farms albeit at sub-clinical levels and significantly impacts swine herd health and profitability. ECO Animal Health believes that Aivlosin offers a cost-effective in-feed medication alternative to longer courses of in-feed antibiotics and is aligned with the prudent use of antimicrobials.”

Aivlosin is available as a premix for administration in feed to provide a dose rate of 4.25mg TVN / kg bodyweight /day for 10 consecutive days, and as Soluble Granules for administration via drinking water at a dose rate of 5mg TVN /kg bodyweight/day for five consecutive days. Both products are used under veterinary prescription.

Aivlosin® is available in a number of international markets under the brand name of Valosin®

Aivlosin® and Valosin® are registered trademarks of ECO Animal Health Ltd., London, United Kingdom.

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Notes to editor:

For further press information please contact Mike Keeler or Nic Daley on +44 (0)20 8647 4467.

ECO/010/15


Responsible treatment of ileitis



Monday 18-02-2013

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Aivlosin® 625mg/g Granules for Pheasants


 

The only antibiotic licensed for ‘Bulgy Eye’ in Pheasants due to Mycoplasma gallisepticum.

Aivlosin® is highly effective and quickly reduces all the classical signs of “bulgy eye”: conjunctivitis, watery eyes, nasal exudates, sinus swelling and depression.

 

Treated birds have increased weight gain and improved feed efficiency over un-medicated birds and a further benefit of using Aivlosin® is that it is highly palatable with no reduction in intake of medicated water during treatment period.

 

Available in a convenient 40g pack and with simple dose calculations for 3 day treatment programmes. Short meat and offal withdrawal period of just 2 days.

 

The excellent solubility of Aivlosin, especially in cold water and short treatment period makes it simple to administer and ideal for use under field conditions.

 

Available in a convenient 40g Sachet which is sufficient to treat 1000kg bodyweight of birds for 1 day.  

 

 

Click Here for more Aivlosin® 625mg/g Granules for Pheasants information



Wednesday 26-01-2011

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Ecomectin 1% Injection Withdrawal Period Update


The withdrawal period for Ecomectin 1% Injection for Cattle within the EU is now extended to 49 days.

The withdrawl period for Ecomectin 1% Injection for all other species within EU and all species (including cattle) for all countries and regions outside of the EU remains the same.





Thursday 17-12-2009

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Aivlosin vs 2 other antibiotics vs M.hyo in pigs


Study aimed to determine the presence of M.hyopneumoniae in pigs that had been treated three different in-feed antibiotics - Aivlosin pig premix, tilmicosin and tiamulin with CTC.

Tamiozzo PJ, Pelliza BR, Carranza AI, Ambrogi A
Department of Animal Pathology, Faculty of Agriculture and Veterinary Medicine, Universidad Nacional de Rio Cuarta, Córdoba, Republic of Argentina.

Aivlosin vs 2 other antibiotics vs M.hyo in pigs



Wednesday 16-12-2009

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Eradication of M.hyo in a sow herd with Aivlosin


Study undertaken to eradicate Mycoplasma hyopneumoniae from a sow farm using Aivlosin.

E.Marco, M.Quiroga, J.M. Bollo, R.Menjón, E.Calvo, M.Donadeu. C.Cia, O.Duran

Eradication of M.hyo in a sow herd with Aivlosin



Wednesday 16-12-2009

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Aivlosin/Chlortet medication vs PRDC in pigs


Study conducted in Friosa, Chile, to evaluate the effect of Aivlosin and Chlortet on pig productive performance and the appearance of respiratory symptoms of PRDC caused by M.hyopneumoniae and Porcine Respiratory and Reproductive Syndrome virus.

Alvaro Ruiz, MV, PhD 

Aivlosin/Chlortet PRDC Chile



Tuesday 25-08-2009

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Aivlosin for control of PPE


Study to demonstrate the efficacy of Aivlosin in the control of proliferative enteropathy (PPE) in pigs experimentally infected with Lawsonia intracellularis.

S.A. Franca, G.S. Machado, M.Blumer, R.M.C.Guedes.

Aivlosin for control of PPE



Monday 13-07-2009

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Aivlosin vs competitor against ileitis in swine


Trial comparing 85 ppm of Aivlosin for 10 days vs 21 days of 110 ppm of tylosin against sub-clinical ileitis/PPE.  The study was well controlled and medication with Aivlosin resulted in a better average daily weight gain (821 g/per day vs 788), statistically shorter time to reach slaughter weight (2 days less), statistically significant improvement in homogeneity of the batch and % of lean meat at slaughter.

P. Pommier, A. Keita, E. Pagot, O. Duran, P.R. Cloet
Published in Revue Méd Vét, 2008, 159, 11, 579-582

Aivlosin vs competitor against ileitis in swine



Tuesday 17-02-2009

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Aivlosin vs competitors against Mycoplasma spp


Article published in International Journal of Poultry Science 7 (11): 1058-1064, 2008 showing the effectiveness of Aivlosin compared with tylosin, tiamulin, erythromycin, oxytetracycline, spectinomycin, linomycin-spectinomycin and enrofloxacin against isolates of Mycoplasma gallisepticum and Mycoplasma synoviae.

Aivlosin vs competitors against Mycoplasma spp



Wednesday 15-07-2009

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Study: tylvalosin for treatment of Swine Dysentery


Study carried out to evaluate the efficacy of the new macrolide tylvalosin for the treatment of an acute field outbreak of Swine Dysentery and compare its efficacy against valnemuline, a well known and highly active pleuromutilin against Brachyspira hyodisenteriae.

Finestra A, Cos R, Menjon R, Bollo J, Baguer A, Tejedor MT , Duran O.

Proceedings of the 2nd Symposium on Veterinary Sciences, Zaragoza, 23-25 October 2008; page 24.

Evaluation of a new antibiotic, tylvalosin, in the treatment of an acute outbreak of Swine Dysentery



Thursday 27-03-2008

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Aivlosin article in Avances Journal


Summary article in Avances Journal of the Anaporc Symposium, where Oliver Duran gave 10 reasons to use Aivlosin.

Aivlosin article in Avances Journal



Thursday 27-03-2008

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Aivlosin article in Produccion Animal


Summary article in Produccion Animal of the Anaporc Symposium, where Oliver Duran gave 10 reasons to use Aivlosin.

Aivlosin article in Produccion Animal



Thursday 13-03-2008

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Aivlosin for the control of ileitis


Studies summarised to show the efficacy of Aivlosin in-feed for the control of ileitis, or Porcine Proliferative Enteropathy.

Aivlosin for the control of ileitis



Thursday 26-11-2009

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Aivlosin for the control of Swine Dysentery


Studies summarised to show the efficacy of Aivlosin in-feed against Brachyspira hyodysenteriae, the causal agent of Swine Dysentery.

Aivlosin for the control of Swine Dysentery



Thursday 13-03-2008

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Activity of Aivlosin against M.hyopneumoniae


Study results indicating Aivlosin's superior capability in the prevention and treatment of Mycoplasma hyopneumoniae, or Swine Enzootic Pneumonia.

Aivlosin vs M. hyopneumoniae



Wednesday 09-04-2008

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XX Congreso Latinoamericano de Avicultura 2007


This major event in the Latin American poultry industry draws several thousand attendees from North, Central and South Americas as well as Europe.

ECO’s large, striking stand in a key location provided a perfect opportunity to discuss Aivlosin with key contacts and to launch the new Aivlosin website and DVDs.





Thursday 14-02-2008

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Transport & accumulation of antibiotics in pigs


Article published in The Pig Journal (2007) 60,26-35 discussing the intracellular accumulation and trans-epithelial transport of Aivlosin, Tylosin and Tilmicosin (A.D. Stuart, T.D. Brown, G. Imrie, J.B. Tasker and A.P.A. Mockett)

Transport & accumulation of antibiotics in pigs



Thursday 14-02-2008

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Aivlosin activity against ORT in poultry


Discussion of studies showing Aivlosin activity against Ornithobacterium rhinotracheale (ORT) in poultry.

Aivlosin activity against ORT in poultry



Thursday 14-02-2008

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Aivlosin for treatment of M.gallisepticum


Treatment of Mycoplasma gallisepticum in chickens with Aivlosin soluble in comparison to Tylan soluble.

Aivlosin for treatment of M.gallisepticum in poultry



Tuesday 30-09-2008

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MIC & MMC of 5 antibiotics against M.synoviae


Study to evaluate in vitro the MIC and MMC of 5 antibiotics to 8 isolated Mycoplasma synoviae strains in poultry.

MIC & MMC of 5 antibiotics against M.synoviae



Tuesday 30-09-2008

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Aivlosin: the new ileitis therapy for pigs


Article written by R.M. Kelly of Schering Plough Animal Health UK, published in The Pig Journal (2007) 59, 178-182, discussing a practitioner's view of Aivlosin as the new Ileitis therapy for pigs.

Aivlosin: the new ileitis therapy for pigs



Wednesday 13-02-2008

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Aivlosin poultry - M.gallisepticum challenge trial


Mycoplasma gallisepticum challenge trial carried out in Brazil measuring clinical and performance parameters.

Aivlosin poultry - M.gallisepticum challenge trial



Tuesday 30-09-2008

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Aivlosin for control of enzootic pneumonia in pigs


Study to investigate the potential of Aivlosin for the prevention and treatment of enzootic pneumonia associated with Mycoplasma hyopneumoniae using an experimental model (Burrows et al 2002)

Aivlosin for control of enzootic pneumonia in pigs



Tuesday 06-11-2007

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Aivlosin posters presented at IPVS Congress 2006


Posters presented at the International Pig Veterinary Society Congress 2006.

1) Use of Aivlosin for the control of Porcine Proliferative Enteropathy in Japan (Tasker et al 2006)

2) Determination of the efficacy of Aivlosin In-Feed for the control of Porcine Proliferative Enteropathy (PPE, Ileitis) in pigs artificially infected with Lawsonia intracellularis (Sims et al 2006)

3) Determination of the dose rate of Aivlosin soluble for the control of artificial infections of Lawsonia intracellularis in pigs (Winkelman et al 2006)

4) The use of Aivlosin In-Feed to control Porcine Proliferative Enteropathy in Denmark (Tasker & Haugegaard 2006)

5) The use of Aivlosin In-Feed for treatment of Swine Dysentery in Ireland (Tasker et al 2006)

Aivlosin posters presented at the IPVS Congress 2006



Monday 05-11-2007

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Transport & accumulation of poultry antibiotics


Study to investigate the uptake and concentration of three macrolide antibiotics in cell types representing enterocytes, epithelial cells and white blood cells in poultry.


Poster presented at the WVPA Congress, Beijing, September 2007.

Transport & accumulation of poultry antibiotics



Monday 05-11-2007

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The use of Aivlosin vs mycoplasmosis


Study to determine the efficacy of tylvalosin (Aivlosin) for the treatment and prevention of mycoplasmosis in field conditions. 

Poster presented at the WVPA Congress, Beijing, September 2007.

Aivlosin granules for oral solution used for the treatment and prevention of mycoplasmosis



Monday 05-11-2007

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Treatment & prevention of endemic pig diseases


Treatment & prevention of endemic pig diseases using the latest generation macrolide antibiotic

Article written by Oliver Duran, DVM, PHD, CERT PM, DECPHM, MRCVS, published in 'Northern Ireland Today', Autumn 2007 issue.

Treatment & prevention of endemic pig diseases



Monday 05-11-2007

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Efficacy of ivermectin on endoparasites in pigs


A study was conducted to evaluate and compare the efficacy of two injectable formulations of ivermectin in the treatment and control of larval and adult stages of Ascaris suum and Oesophagostomum spp in experimentally infected pigs.

Article written by FHM Borgsteede et al, published in Veterinary Parasitology issue 146 (2007)

Efficacy comparison of ivermectin on endoparasites in pigs




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